Acyl bromides
Sigma Aldrich (4-CHLORO-3-PYRIDINYL)METHANOL
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich Benzoyl bromide
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Selleck Chemical LLC Ipratropium Bromide S1683-50mg
Ipratropium Bromide is an antagonist of M3 type muscarinic acetylcholine receptors used for the treatment of chronic obstructive pulmonary disease (COPD)
Apexbio Technology LLC Cetrimonium Bromide (CTAB) 57-09-0 10mM (in 1mL DMSO)
Cetrimonium Bromide (CTAB) (CAS 57-09-0) is a cationic surfactant that exerts its biological activity primarily through disruption of microbial membrane integrity via electrostatic interactions with negatively charged membrane components CTAB demonstrates antimicrobial activity by inhibiting microbial growth in in vitro assays Commonly employed in molecular biology protocols CTAB facilitates nucleic acid extraction through cellular lysis precipitation and purification particularly in plant genomic DNA isolation Additionally it is useful for antiseptic formulation studies nanoparticle synthesis and pharmaceutical research including drug delivery system development and stability studies
Medchemexpress LLC Umeclidinium bromide | 869113-09-7 | MFCD18782614 | 508.49 | 1 G
Umeclidinium bromide is a novel mAChR antagonist, demonstrating high affinity for cloned human M1-M5 mAChRs with Ki values ranging from 0.05 to 0.16 nM. It is a potent agent that exhibits slow functional reversibility at cloned human M3 mAChRs and endogenous mAChRs in isolated human bronchus. This compound is suitable for research in various disease areas including neurological, eye or ear disease, cancer, inflammation or immune system disease, neurodegenerative disease, and Parkinson's disease.
- Novel mAChR antagonist
- High affinity for human M1-M5 mAChRs (Ki 0.05-0.16 nM)
- Inhibits human ether-a-go-go-related gene channel tail current with an IC50 of 9.4 μM
- Demonstrates slow functional reversibility at human M3 mAChRs
- Applicable for research in neurological, ocular, oncological, inflammatory, and neurodegenerative conditions
Medchemexpress LLC Mepenzolate bromide | 76-90-4 | 99.9% | 420.34 | 100 MG
Mepenzolate bromide is an orally administered muscarinic receptor antagonist with Kis of 0.68 and 2.6 nM for hM2R and hM3R, respectively. It can be used to suppress gastrointestinal hypermotility associated with irritable bowel syndrome. Mepenzolate bromide is also a GPR109A inhibitor.
- Muscarinic receptor antagonist
- GPR109A inhibitor
- Exerts anti-inflammatory effect via a muscarinic receptor-independent mechanism
- Bronchodilatory effect via a muscarinic receptor-dependent mechanism
- Subtype-non-specific muscarinic antagonist
- Beneficial effects in a mouse model of chronic obstructive pulmonary disease (COPD)
Apexbio Technology LLC Aclidinium Bromide 320345-99-1 10mg
Aclidinium Bromide (CAS 320345-99-1) is a long-acting muscarinic antagonist (LAMA) that selectively inhibits muscarinic acetylcholine receptors In binding assays it demonstrates high affinity for M1 M5 receptor subtypes with Ki values of 0 10 0 21 nM Functional studies reveal greater potency at endogenous M2 and M3 receptors with EC50 values of 17 4 nM and 5 3 nM respectively In vivo aclidinium bromide produces a concentration-dependent inhibition of acetylcholine-induced bronchoconstriction (EC50 2 5 23 1 g/mL in anesthetized guinea pigs) and suppresses pilocarpine-induced salivation in rats (EC50 38 g/kg) This compound is widely utilized in respiratory research for evaluating airway smooth muscle modulation via muscarinic receptor antagonism
Medchemexpress LLC 3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-2'-methyluridine | 863329-65-1 | 99.4% | 468.43 | 100 MG
3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-2'-methyluridine is a drug intermediate utilized in the synthesis of various active compounds.
- Used in the synthesis of various active compounds.
- Serves as a drug intermediate.
Apexbio Technology LLC Rocuronium Bromide 119302-91-9 100mg
Rocuronium Bromide (CAS 119302-91-9) is an aminosteroid compound that functions as a non-depolarizing neuromuscular blocking agent It acts by competitively antagonizing nicotinic acetylcholine receptors at the neuromuscular junction thereby inhibiting acetylcholine-induced depolarization and subsequent muscle contraction In research settings Rocuronium Bromide is utilized to investigate neuromuscular transmission and to model pharmacological blockade of skeletal muscle activity supporting studies in anesthesia muscle physiology and synaptic transmission mechanisms